Study of Intrathecal Clonidine to Magnesium Sulfate as Adjuvants to Hyperbaric Bupivacaine in Subarachnoid Block in Tertiary Care Centre

Background: Spinal anaesthesia is the most preferred regional technique as it easy to perform,economical and produces rapid onset of complete muscle relaxation. The aim intrathecal localanaesthetic provide adequate sensory motor block necessary for all infra umbilical surgeries.Aims Objectives: study compare Onset Duration Sensory Block; andDuration Motor Block other factors in two groups i.e., Hyperbaric Bupivacaine 0.5% with Clonidine 30μg&Hyperbaric Magnesium sulphate 50 mg when given intrathecally.Materials Methods: A Comparative three group randomized clinical 90 patients 30 patientsin Group C (Clonidine), M (Magnesium) N (Normal saline) studythe block, changes hemodynamics side effects.Results: Our has demonstrated that Intrathecal clonidine (30 mcg) prolonged post-operative analgesia alongwith earlier duration blockade compared both magnesium (50 mg)and control.Intrathecal mg) also increased analgesic control but wasassociated delayed control.Conclusion: can be a good alternative adjuvant hyperbaric bupivacaine comparedto others like fentanyl, magnesium, midazolam, ketamine etc. provides early motorblockade analgesia.